Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-08-21
1999-11-30
Davenport, Avis M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530300, 530324, 436 86, 436 63, A61K 3800, C07K 700, G01N 3300, G01N 3348
Patent
active
059943050
ABSTRACT:
A method of producing analgesia in nociceptive and neuropathic pain is disclosed. The method includes administering to a subject an omega conopeptide which is characterized by its ability to (a) inhibit electrically stimulated contraction of the guinea pig ileum, and (b) bind selectively to omega conopeptide MVIIA binding sites present in neuronal tissue. Also disclosed are novel omega conotoxin peptides effective in producing analgesia.
REFERENCES:
patent: 5587454 (1996-12-01), Justice et al.
patent: 5824645 (1998-10-01), Justice et al.
patent: 5859186 (1999-01-01), Justice et al.
Gohil Kishor Chandra
Justice Alan
Miljanich George P.
Singh Tejinder
Valentino Karen L.
Davenport Avis M.
Dehlinger Peter J.
Elan Pharmaceuticals Inc.
Stratford Carol A.
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