Method of treating hypoparathyroidism with (20S) vitamin D compo

Details Method of treating hypoparathyroidism with (20S) vitamin D compo Method of treating hypoparathyroidism with (20S) vitamin D compo

1993-11-03

1996-09-03

Prior, Kimberly J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

552653, A61K 3159

Patent

active

055523927

ABSTRACT:
The invention discloses a method for treating hypoparathyroidism with vitamin D.sub.3 analogs of the following formula: ##STR1## The methyl group in these compounds which is normally attached to the side chain at carbon 20 has been exchanged with the hydrogen atom attached to carbon 20 to form the 20-epi configuration. The compounds are useful for the treatment of hypoparathyroidism because of their high activity for mobilizing calcium form the bone.

REFERENCES:
patent: 4421690 (1983-12-01), Partridge et al.
patent: 4594432 (1986-06-01), Baggiolini et al.
patent: 4613594 (1986-09-01), Baggiolini et al.
patent: 5401731 (1995-03-01), Calverley et al.

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