Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-09-06
1997-11-18
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 21, 530350, 530300, 530418, A61K 3817, C07K 130, C07K 1400
Patent
active
056887620
ABSTRACT:
A process of inhibiting the renin angiotensinogen angiotensin mechanism and treating hypertension administers a blood pressure lowering amount of a protease inhibitor peptide obtained by the cleavage of pepsinogen to a mammal. Hypertension is also treated by administering a blood pressure lowering amount of a stomach mucosa extract from animal origin. The extract is obtained under mild conditions in an extracting solvent containing an acidifying agent.
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patent: 5134123 (1992-07-01), Branca et al.
Structural Changes Associated With the Conversion of the Pepsinogen to Pepsin, Biochemica et Biophysica Acta, vol. 22, pp. 537-543 (1956) Vunakis et al.
Structural Changes Associated With the Conversion of Pepsinogen to Pepsin, Biochemica et Biophysica Acta, vol. 23, pp. 600-605 (1957) Vunakis et al.
Vunkakis et al. `Structural Changes Associated With the Conversiono F Pepsinogen to Pepsin`, Biochemica et Biophysica Acta, vol. 22, pp. 537-543, 1956.
Vunkakis et al. `Structural Changes Associated With the Conversiono F Pepsinogen to Pepsin`, Biochemica et Biophysica Acta, vol. 23, pp. 600-608, 1957.
Gupta Anish
Tsang Cecilia J.
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