Method of treating hypertension using a composition containing a

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

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514 12, 514 21, A61K 3800

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active

059228393

ABSTRACT:
A process of inhibiting the renin angiotensinogen angiotensin mechanism and treating hypertension includes the step of administering a blood pressure lowering amount of a dried stomach mucosa and acidifying agent.

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"Structural Changes Associated with the Conversion of Pepsinogen to Pepsin, I. The N-Terminal Amino Acid Residue and Amino Acid Composition of the Pepsin Inhibitor", Vunakis et al., Biochim. Biophys. Acta, vol. 22, pp. 537-543, 1956.
"Structural Changes Associated with the Conversion of Pepsinogen to Pepsin, II. The N-Terminal Amino Acid Residues of Pepsin and Pepsinogen; The Amino Acid Composition of Pepsinogen", Vunakis et al., Biochim. Biophys. Acta, vol. 23, pp. 600-605, 1957.

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