Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1995-04-11
1996-04-30
Prior, Kimberly J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
552653, A61K 3159, C07C40100
Patent
active
055125549
ABSTRACT:
Compounds of the formula ##STR1## wherein R is hydrogen, hydroxy, or fluorine, and X is H.sub.2 or .dbd.CH.sub.2 are useful as agents for the treatment of hyperproliferative disorders of the skin such as psoriasis, as agents for the treatment of cancer, such as, leukemia, and as agents for the treatment of sebaceous gland diseases, such as, acne and seborrheic dermatitis.
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Baggiolini, deceased Enrico G.
Shiuey Shian-Jan
Uskokovic Milan R.
Ciambrone Coletti Ellen
Gould George M.
Hoffmann-La Roche Inc.
Johnston George W.
Prior Kimberly J.
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