Method of treating human EGF receptor-expressing gliomas using r

Details Method of treating human EGF receptor-expressing gliomas using r Method of treating human EGF receptor-expressing gliomas using r

1990-04-24

1995-11-28

Hutzell, Paula K.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to antibody or antibody fragment or immunoglobulin;...

53038822, 4241381, 4241411, 4241431, 424 91, A61K 5110, A61K 39395, C07K 1630

Patent

active

054705711

ABSTRACT:
Monoclonal antibody 425 having properties particularly beneficial for anti-tumor therapy has been raised. MAb 425 antibody binds to EGF-receptors and inhibits their bioactivities. The amount of binding of the antibody to cancer cells can be increased by treatment of the cells with lymphokine preparations. Radiolabeled MAb 425 is used for treatment of EGF receptor-expressing gliomas.

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