Method of treating horses to inhibit or reduce increases in cren

Details Method of treating horses to inhibit or reduce increases in cren Method of treating horses to inhibit or reduce increases in cren

1980-11-26

1983-05-17

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424250, A61K 3152, A61K 31495

Patent

active

043839975

ABSTRACT:
A marked increase in red blood cell shape transformations into abnormal cell types, such as crenated erythocytes, known to have a reduced fluidity and membrane flexibility (deformability), and an increased fragility and viscosity has been found in animals such as horses following physical activity. The condition is treated by administering to the animal a compound which inhibits influx of extracellular Ca.sup.++ into red blood cells, or enhances the ATP content of ATP-depleted red blood cells.

REFERENCES:
DeCree et al.-Chem. Abst. vol. 91 (1979) p. 168,649w.
Flameng et al.-Chem. Abst. vol. 91 (1979) p. 168,650q.
Heidbreder-Chem. Abst. vol. 84 (1976) p. 69,576u.
Jageneau et al.-Chem. Abst. vol. 77 (1972) p. 70372m.
Detry et al.-Chem. Abst. vol. 85 (1976) p. 104,151w.

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