Method of treating herpes simplex virus infection

Details Method of treating herpes simplex virus infection Method of treating herpes simplex virus infection

1991-01-29

1992-11-24

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514553, 514577, 514656, 514660, A01N 3302, A61K 3113, A61K 3121, A61K 31135

Patent

active

051661730

ABSTRACT:
A method of inhibiting cell infection by herpes simplex virus-1 or -2. The method includes contacting the virus with a macrocyclic chromotropic acid compound, in an amount effective to inhibit cell infectivity of the virus.

REFERENCES:
Akerfeldt, S., et al., J. Med. Chem. 14(7):596-600 (1971).
Hansch, C. and Leo, A. Chapter VI, Table VI-1, in "Substituent Constants for Correlation Analysis in Chemistry and Biology" Wiley, Ed., New York 1979 pp. 48-54.
Poh, B-L and Lim, C. S., Tetrahedron 46, No. 10 (1990) 3651-3658.
Poh, B-L et al., Tetrahedron 46, No. 12, (1990) 4379-4386.
Poh, B-L et al., Tetrahedron 30, No. 8 (1989) 1005-1008.
Merluzzi, V. J. et al., Science 250, (Dec. 7 1989) 1411-1413.

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