Method of treating helminthiasis by parenteral administration of

Details Method of treating helminthiasis by parenteral administration of Method of treating helminthiasis by parenteral administration of

1978-02-16

1979-03-20

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548306, A61K 31415

Patent

active

041454316

ABSTRACT:
A method is provided for treating or inhibiting helminthiasis by parenterally or topically administering sulfide or sulfoxide derivatives of benzimidazoles having the structure ##STR1## wherein R.sup.1 is lower alkyl or phenyl-lower alkyl, R.sup.2 and R.sub.3 may be the same or different and are hydrogen or lower alkyl, Z is ##STR2## or R.sup.4 --C.tbd.C--, R.sup.4, R.sup.5 and R.sup.6 may be the same or different and are hydrogen, lower alkyl, or phenyl, and m is 0 to 3, n is 0 to 3, m + n being .ltoreq. 5, and p is 0 or 1. Pharmaceutical compositions for use in the above method are also provided.

REFERENCES:
patent: 3929821 (1975-12-01), Beard et al.
patent: 4002640 (1977-01-01), Beard et al.

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