Method of treating heart failure with endothelin antagonists

Details Method of treating heart failure with endothelin antagonists Method of treating heart failure with endothelin antagonists

1998-08-11

2000-07-11

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514249, 514258, 514299, A61K 31495, A61K 31505, A61K 3144

Patent

active

060873604

ABSTRACT:
A method for preventing and/or treating heart failure and ventricular dysfunction in a warm blooded animal comprising administering to the warm blooded animal a therapeutically effective amount of an endothelin antagonist of the formula: as defined herein.

REFERENCES:
patent: 5389620 (1995-02-01), Ishikawa et al.
patent: 5658943 (1997-08-01), Berryman et al.
patent: 5668176 (1997-09-01), Bagley et al.
patent: 5834483 (1998-11-01), Lynch, Jr. et al.

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