Method of treating endotoxin effects with 2-haloadenosine nucleo

Details Method of treating endotoxin effects with 2-haloadenosine nucleo Method of treating endotoxin effects with 2-haloadenosine nucleo

1993-10-15

1996-05-14

Kunz, Gary L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514921, A61K 3170, C07H 19167

Patent

active

055167624

ABSTRACT:
A method of treating a mammal exposed to endotoxin in order to reduce the detrimental effects of said endotoxin, comprising administering to said mammal a therapeutically effective amount of a 2-halo-adenosine nucleotide analog. 2-Cloro-ATP is the preferred species of the 2-halo-adenosine nucleotide. The nucleotide used in this treatment inhibits lipo-polysaccharide-induced GTPase activity.

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