Method of treating Down Syndrome

Details Method of treating Down Syndrome Method of treating Down Syndrome

2011-08-09

2011-08-09

Henley, III, Raymond (Department: 1629)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S731000

Reexamination Certificate

active

07994210

ABSTRACT:
The present invention relates to methods of treating of Down syndrome in a person using compounds of the invention.

REFERENCES:
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patent: WO 03/082270 (2003-10-01), None
patent: WO 2004/101603 (2004-11-01), None
Cure research for Alzheimer's Disease (visited Jan. 7, 2004) http://wrongdiagnosis.com/a/alzheimers—disease/research.htm.
Prasher et al., A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Down syndrome and Alzheimer's disease—Pilot Study, International Journal of Geriatric Psychiatry, 2002, pp. 270-278, vol. 17.
Shaw et al., “Phenserine regulates translation of beta-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development,” PNAS, Jun. 19, 2001, pp. 7605-7610, vol. 98, No. 13.
Patel, et al., Abstract, “Phenserine, a novel acetylcholinesterase inhibitor, attenuates impaired learning of rats in a 14-unit T-maze induced by blockage of the N-methyl-D-aspartate receptor,” Jan. 1998, pp. 171-176, vol. 9, No. 1.

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