Method of treating cystic fibrosis using a tachykinin receptor a

Details Method of treating cystic fibrosis using a tachykinin receptor a Method of treating cystic fibrosis using a tachykinin receptor a

1995-06-27

1998-11-03

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 14, 514 15, 514354, 514355, 514415, 514210, 514352, 514396, 514364, 514430, 514431, 514432, 514444, 514449, 514451, 514461, 514475, 514481, 514485, 530327, 530328, A61K 3800, A61K 3144, A01N 3418, A01N 4340

Patent

active

058308547

ABSTRACT:
Tachykinin receptor antagonists are useful for the treatment of cystic fibrosis.

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Regulatory Peptides, (1988), vol. 22, 127, "Pharmacological Specificity of Synthetic Peptides as Antagonists at Tachykinin Receptors" by A.T. McKnight et al.
Chung, K. Fan, Effects of nedocromil sodium on airway neurogenic mechanisms, J. Allergy Clin. Immunol., 98 (5, Pt. 2), pp. S112-S117, 1996.
Javdan, et al., Nedocromil sodium reduces allergen-induced plasma extravasation . . . , Allergy (Copenhagen), vol. 50, No. 10, pp. 825-829, 1995.
Sekizawa, et al., Enkephalinase inhibitor potentiates mammalian tachykinin-induced contraction . . . , J. Pharmacol. Exp. Ther., vol. 243, No. 3, pp. 1211-1217, 1987.

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