Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-07-02
2000-09-19
Higel, Floyd D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142305, 5142358, 514396, 514397, 514398, 514399, 514400, 544 585, 544 62, 544105, 544139, 5483117, 5483365, 5483415, 5483431, 5483435, A61K 3154, A61K 31541, A61K 315415, A61K 315377, A61K 31538, A61K 314166
Patent
active
061212601
ABSTRACT:
Certain diaryl imidazoles act as partial agonists or antagonists for NPY receptors, in particular NPY 5 receptors. They are of use, for example in treating loss of appetite. Such compounds bear aryl groups in the 2 position. Many of the compounds are novel.
REFERENCES:
patent: 3297710 (1967-01-01), Silversmith
patent: 3657441 (1972-04-01), Jensen et al.
patent: 4134983 (1979-01-01), Baldwin
patent: 4665023 (1987-05-01), Deneke et al.
patent: 4757124 (1988-07-01), Koyanagi et al.
patent: 4758639 (1988-07-01), Koynagi et al.
patent: 4853383 (1989-08-01), Baldwin et al.
patent: 5017467 (1991-05-01), Masukawa et al.
patent: 5292669 (1994-03-01), Guder et al.
patent: 5296609 (1994-03-01), McCort et al.
patent: 5498301 (1996-03-01), Hirao et al.
patent: 5620999 (1997-04-01), Weier et al.
Lombardino, Joseph G., et al. "Preparation and Antiinflammatory Activity of Some Nonacidic Trisubstituted Imidazoles." Journal of Medicinal Chemistry, vol. 17, No. 11 (1974, pp. 1182-1188 XP-002080630.
Suzuki, Mamoru et al. "Syntheses of 2-Aryl-4-(3-thienyl)imidazole Derivatives with Antiinflammatory Properties." Chemical and Pharmaceutical Bulletin, vol. 34, No. 8 (1986) pp. 3111-3120 XP-002080631.
Baldwin, J. J., et al. ".beta.-Adrenergic Blocking Agents with Acute Antihypertensive Activity." Journal of Medicinal Chemistry, vol. 22, No. 6 (1979) pp. 687-694 XP002080632.
Blum Charles A.
Elliot Richard L.
Hammond Marlys
Hutchison Alan
Thurkauf Andrew
Higel Floyd D.
Neurogen Corporation
Pfizer Inc.
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