Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Patent
1994-09-27
1997-07-01
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
424 149, 424 169, 4241301, 4241551, 530837, 530808, 530809, 5303888, 436501, 436512, 436548, 436808, 436813, 935 95, 935103, 935106, A61K 5100, A61K 4900, A61K 3514
Patent
active
056435509
ABSTRACT:
This invention provides a method of imaging a colorectal carcinoma lesion in a human patient which comprises administering to the patient a monoclonal antibody capable of binding to a cell surface antigen associated with the colorectal carcinoma lesion and which is labeled with an imaging agent under conditions so as to form a complex between the monoclonal antibody and the cell surface antigen, imaging any complex so formed, and thereby imaging the colorectal carcinoma lesion.
This invention also provides a monoclonal antibody designated AS 33 (ATCC Accession No. HB 8779) and the hybridoma which produces it.
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Divgi Chaitanya R.
Oettgen Herbert F.
Old Lloyd J.
Real Francisco X.
Sakamoto Jun-ichi
Hartley Michael G.
Hollinden Gary E.
Sloan-Kettering Institute for Cancer Research
White John P.
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