Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-10-10
1999-10-19
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514241, 514242, 514252, 514267, 514359, 514363, 514365, 514372, 514374, 514378, 514383, 514451, 514444, 514473, 514499, 514461, A61K 3134
Patent
active
059689749
ABSTRACT:
This invention is directed to a method of retarding or preventing the transformation of a colonic adenoma to a colonic adenocarcinoma comprising the administration to a patient with FAP or a patient with one or more of said adenomas a non-toxic therapeutically effective amount of NSAID, said amount effective to inhibit the PGHS-2 in said adenoma. The preferred method comprises the administration of a specific PGHS-2 inhibiting agent as defined herein.
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Evans Jilly
Kargman Stacia
Simon Thomas J.
Billups Richard C.
Chang Ceila
Merck & Co. , Inc.
Panzer Curtis C.
Rose David L.
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