Method of treating chloroquine-resistant malaria with aminoquino

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546163, A61K 3147, C07D21544, C07D21546

Patent

active

055960022

ABSTRACT:
Novel aminoquinoline derivatives of the general formula ##STR1## are described. Also described are methods for the treatment of malaria pathogens, particularly chloroquine-resistance malaria pathogens with compounds of formula I or the pharmaceutically acceptable salts and hydrolyzable esters thereof.

REFERENCES:
patent: 2594419 (1952-04-01), Geschickter
patent: 3346579 (1967-10-01), Sheehan
Singh, "Antimalarials . . . ", J Med Chem, vol. 14, No. 4, pp. 283-286, 1971.

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