Method of treating certain tumors using illudin analogs

Details Method of treating certain tumors using illudin analogs Method of treating certain tumors using illudin analogs

1990-10-31

1995-08-08

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

A61K 3112

Patent

active

054399424

ABSTRACT:
A method of inhibiting certain tumor cell growth in a subject is provided comprising contacting the tumor with a therapeutic amount of an illudin S or illudin M analog having the structure ##STR1## wherein the analog is capable of inhibiting tumor cell growth without excessive toxicity to the subject and wherein

REFERENCES:
McMorris et al, Tetrahedron, vol. 45 No. 17, pp. 5433-5440, 1989.
Kelner et al., Cancer Research 47:3186-3189 (1987).

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