Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1980-05-20
1981-11-24
Fagelson, Anna P.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31215
Patent
active
043024718
ABSTRACT:
The present invention relates to a method of inducing a response dopamine-like in an animal having impaired cardiovascular and renal functions, comprising administering to said animal an effective amount of a compound having the general formula: ##STR1## wherein R is a secondary or tertiary alkyl radical having from 3 to 7 carbon atoms, and their salts with nontoxic organic and inorganic acids.
In particular, the present invention relates to a method of treating cardiac and renal failures comprising administering to a patient suffering therefrom an effective amount of a compound having the above-identified general formula, in suitable pharmaceutical preparations.
REFERENCES:
Melloni et al., "Clinical Pilot Trail on SB7505", Current Clinical Research, vol. 26, No. 4, Oct. 1979, pp. 466-470.
Cicchetti et al., "Behavior of Diuresis, . . . After SB7505", Current Clinical Research, vol. 27, No. 5, pp. 741-747, May 1980.
Melloni et al., "Effects of SB7505 on Blood Pressure", Current Therapeutic Research, vol. 25, No. 3, pp. 406-414, Mar. 1979.
Arzneim, Forsch./Drug Res., Dei Cas et al., "Non-Invasive Evaluation of Ventricular Function . . . in Man", 30 (I), No. 3, pp. 498-500, (1980).
La Nouvelle Presse Medical, "Effects D'un Derive de la Dopamine Actif par voie Orale sur L'Excretion Renal", p. 453, Feb. 9, 1980.
Casagrande Cesare
Ferrari Giorgio
Fagelson Anna P.
Simes Societa Italian Medicinali e Sintetici S.p.A.
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