Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-01-24
2006-01-24
Cook, Rebecca (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S255010, C514S255020, C514S449000, C514S459000, C514S471000, C514S616000
Reexamination Certificate
active
06989383
ABSTRACT:
The present invention relates to methods of treating cancer using a combination of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at lest two therapeutic agents selected from a group consisting of a compound which is an antineoplastic agent and a compound which is an inhibitor or prenyl-protein transferase. The invention also relates to methods of preparing such compositions.
REFERENCES:
patent: 5856326 (1999-01-01), Anthony et al.
patent: 5912154 (1999-06-01), Ferro-Novick et al.
patent: 0 456 180 (1991-11-01), None
patent: 0 618 221 (1994-05-01), None
patent: 0 670 314 (1995-03-01), None
patent: 0 856 315 (1997-02-01), None
patent: WO 97/01275 (1997-01-01), None
patent: WO 97/17070 (1997-05-01), None
Slichenmyer et al., Anti-Cancer Drugs (1991), 2(6), 519-30 abstract only.
Moasser, et al., Farnesyl transferase inhibitors cause enchanced mitotic sensitivity to taxol and epothilones, Feb. 1998, Proc. Natl. Acad. Sci. USA, vol. 95, pp. 1369-1374Molecular Pharmacology, vol. 47, pp. 1106-1111 (1995).
Danesi, Paclitaxel (Taxol) Inhibits Protein Isoprenylation and Induces Apoptosis in PC-3 Human Prostate Cancer Cells, 1995, Molecular Pharmacology, vol. 47, pp. 1106-1111.
Gibbs Jackson B.
Graham Samuel L.
Kohl Nancy
Moasser Mark M.
Oliff Allen I.
Cook Rebecca
Law Offices of Albert Wai-Kit Chan LLC
Sloan-Kettering Institute For Cancer Research
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