Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1995-03-23
1997-04-01
Loring, Susan A.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
4241501, 4241411, 4241561, 4241641, 53038823, 5303882, 5303884, 53038885, A61K 39395, A61K 4900, C07K 1624, C07K 1628
Patent
active
056163215
ABSTRACT:
Bacterial meningitis infection in a mammal is treated by intravenous infusion of a therapeutically effective amount of a monoclonal antibody which binds to tumor necrosis factor alpha and an antibiotic. Treatment can be initiated up to five hours after bacterial challenge and the antibiotic is preferably selected from cephalosporins and aminoglycosides.
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Collins Michael S.
Hector Richard F.
Baran Alexandra J.
Bayer Corporation
Enayati Elizabeth F.
Giblin James A.
Loring Susan A.
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