Method of treating arthritus or inflammation with IL-1.beta. or

Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin

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424 851, 514 2, 514 8, 514 21, 514825, 514886, A61K 3702

Patent

active

053426142

ABSTRACT:
Interleukin-1.beta. (IL-1.beta.) and derivatives, and their pharmaceutical compositions for use in treating arthritis or inflammation.

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Dinarello, Review of Infectious Disease, vol. 6, 1984, pp. 51-95.
Oppenheim et al, Immunology 7, 1986, pp. 45-56.
Durum et al. Ann. Rev. Immunol. 1985, vol. 3, pp. 263-287.
Postlethwaite et al, J. Experi. Med. 157, 1983, pp. 801-806.
Mizel, PNAS 78, 1981, pp. 2474-2477.
Dayer et al, Eur. J. Immunol. 1984, pp. 898-901 vol. 14.

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