Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-04-22
2008-04-22
Kim, Jennifer (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S419000, C514S367000
Reexamination Certificate
active
07361681
ABSTRACT:
The present invention relates to the treatment of amyotrophic lateral sclerosis (ALS) and/or the improvement of motor function in individuals in need of such improvement using a melatonin compound or a pharmaceutical salt of the melatonin compound.
REFERENCES:
patent: 3642994 (1972-02-01), Fernando
patent: 5591768 (1997-01-01), Lewy et al.
patent: 5700828 (1997-12-01), Federowicz et al.
patent: 5780489 (1998-07-01), Brooks
patent: 6004991 (1999-12-01), Fourtillan et al.
patent: 6274615 (2001-08-01), Pappolla et al.
patent: 6353015 (2002-03-01), Oxenkrug et al.
patent: 6436984 (2002-08-01), Ducrocq et al.
patent: 6458384 (2002-10-01), Jaenicke et al.
patent: 6469049 (2002-10-01), Meyerhoff et al.
Bowling et al. Bioenergetic and oxidative stress in neurodegenerative diseases. Life Sciences, 1995, vol. 56, No. 14, pp. 1151-1171.
J. Pineal Research, 2002; 33:186-187, Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): high tolerability of daily oral melatonin administration in ALIS patients.
Iacovitti, et al. Brain Research, 768 (1997) 317-326, Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress.
Cazevieille, et al., Brain Research, 768 (1997) 12-24, Melatonin protects primary cultures of rat cortical neurons from NMDA excitotoxicity and hypoxial/reoxygenation.
General Anti Oxidant Information, Feb. 1998, www.home.goulbum.net.au/shack/antioxidants.htm.
Ehrenreich Hannelore
Hardeland Ruediger
Nave Klaus-Armin
Weishaupt Jochen
Kim Jennifer
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
SYGNIS Bioscience GmbH & Co. KG
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