Method of treating a water soluble capsule

Plastic and nonmetallic article shaping or treating: processes – With printing or coating of workpiece – Coating or impregnating workpiece before molding or shaping...

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53407, 53477, 128261, 128272, 206528, 264232, 264238, 264344, 424 37, 427 3, 427338, A61M 300

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042786339

ABSTRACT:
A gelatin capsule is formed with an elongated portion and a bulb portion with a medicinal material therein for supply to a body through inserting the elongated portion in a body orifice. The elongated portion is treated with a hardening agent which withdraws water and/or glycerin from the elongated portion of the capsule so that the elongated portion has sufficient rigidity for insertion within the body orifice. The hardening agent can be a polymer of a glycol, which is preferably polyethylene glycol, an inorganic drying agent such as silica gel or phosphorus pentoxide, an alcohol, or a ketone, such as acetone, for example. When a polymer of a glycol is utilized as the hardening agent, the polymer of a glycol can remain on the elongated portion to function as a lubricant when the elongated portion is inserted in the body orifice. Furthermore, the polymer of a glycol can include an anesthetic for deadening the nerves around the body orifice. To prevent the polymer of a glycol from flowing to the bulb portion to harden it when the polymer of a glycol remains on the elongated portion, the viscosity of the polymer of a glycol is preferably selected so that it will not flow at room temperature although the coating of the polymer of a glycol could be coated with paraffin or a mechanical barrier to prevent this or the bulb portion could be coated with paraffin to prevent the polymer of a glycol from affecting the soft bulb portion or a mechanical barrier could be provided between the elongated and bulb portions.

REFERENCES:
patent: 1527659 (1925-02-01), Wilkie
patent: 2064143 (1936-12-01), Belton et al.
patent: 2318185 (1943-05-01), Schreyer
patent: 2512115 (1950-06-01), Senff
patent: 2712672 (1955-07-01), Calcagno
patent: 3006760 (1961-10-01), Dersch et al.
patent: 3379554 (1968-04-01), Brindamour
patent: 3616101 (1971-10-01), Satchell et al.
"Encyclopedia of Chemical Technology"-Kirk-Othmer-Silica Gell, vol. 12, 1968, pp. 345-347.
"Encyclopedia of Chemical Technology"-Kirk-Othmer-Phosphorus Pentoxide, vol. 15, 2-1969, pp. 311-315.

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