Method of treating a vascular obstructive lesion resulting from

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514264, 514265, 514307, A61K 3152, A61K 3147

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active

048143367

ABSTRACT:
A new method of treatment is disclosed for a vascular obstructive lesion resulting from restricted blood circulation, characterized by an erythrocyte pathology, in an effected animal subject. The new method involves the administration of 1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinolinium-theophylli ne-7-acetat e, in a dosage and at a rate sufficient to maintain a blood concentration of at least 0.5 to at most 3 .gamma./ml, calculated on the basis of 1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinoline.

REFERENCES:
patent: 4035366 (1977-07-01), Szentmiklosi et al.
Aviado et al, Pharmacology of Pentoxifylline: A Hemorheologic Agent for the Treatment of Intermittent Claudication, Angiology-Journal of Vascular Diseases, pp. 407-417 (Jul. 1984).

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