Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds antigen or epitope whose amino acid sequence is...
Reexamination Certificate
2004-10-20
2010-12-14
Landsman, Robert (Department: 1646)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds antigen or epitope whose amino acid sequence is...
C424S130100, C530S387900
Reexamination Certificate
active
07850967
ABSTRACT:
Therapeutic regimens for administration of BAFF antagonists for treatment of immunologic and related disorders are described. Regimens involve a short-term BAFF antagonist administration course followed by an extended no-treatment period prior the round of administration.
REFERENCES:
patent: 5445940 (1995-08-01), Brenner et al.
patent: 7112410 (2006-09-01), Ruben et al.
patent: 7112421 (2006-09-01), Ambrose et al.
patent: WO 02/24909 (2002-03-01), None
Sevach (Fundamental Immunology, Paul ed, Lippincott-Raven Philadelphia, PA, 1999, chapter 34 pp. 1089-1103, 1105-1125.
Cohen, (Fundamental Immunology, Paul ed, Lippincott-Raven Philadelphia, PA, 1999, chapter 33 pp. 1067-1088.
Schwartz et al in “Fundamental Immunology”, Paul ed Raven Press, NY. NY. 1989, p. 837.
International Search Report for PCT/US2004/034514, mailed Apr. 6, 2005 from the International Searching Authority of the European Patent Office.
Gross et al., “TACI and BCMA Are Receptors for a TNF Homologue Implicated in B-Cell Autoimmune Disease,”Nature, 404:995-999 (2000).
Kayagaki et al., “BAFF/BLyS Receptor 3 Binds the B Cell Survival Factor BAFF Ligand through a Discrete Surface Loop and Promotes Processing of NF-κB2,”Immunity, 10:515-524 (2002).
Pelletier et al., “Comparison of Soluble Decoy IgG Fusion Proteins of BAFF-R and BCMA as Antagonists for BAFF,”J. Bio. Chem., 278:33127-33133 (2003).
Stohl, W., “A Therapeutic Role For BLyS Antagonists,”Lupus, 13:317-332 (2004).
Kalled Susan
Rao Sambasiva
Biogen IDEC MA Inc.
Chandra Gyan
Finnegan Henderson Farabow Garrett & Dunner LLP
Landsman Robert
LandOfFree
Method of treating a patient having an autoimmune disorder... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of treating a patient having an autoimmune disorder..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of treating a patient having an autoimmune disorder... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4173800