Method of treating a nerve-related vision disorder in a...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C530S303000, C424S427000

Reexamination Certificate

active

07829532

ABSTRACT:
This invention provides reagents and methods for delivering insulin, insulinomimetic agents, and the like to a vertebrate eye via subconjunctival routes, sub-Tenon's routes, or intravitreal routes for treatment of nerve-related vision disorders such as diabetic retinopathy, and formulations useful in the practice of the disclosed methods.

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Bosco et al., Invest. Opthal. Vis. Sci. 49: 1437-1446, 2008.
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J. Ambatl; C. Canakls; J.Miller; E. Gragoudos; A. Edwards; D. Wolssgold; I. Kim; F. Delari; A. Adamls, “Diffusion of High Molecular Weight Compounds through Sclora,” IOVS, Apr. 2000, vol. 41, No. 5. pp. 1181-1185.
J. Ambatl; E. Gragoudas; J. Miller; T. You; K. Miyamoto; F. Delori; A. Adamls, “Transscloral Delivery of Bioactive Protein to the Chorold and Retina,” IVOS, Apr. 2000, vol. 41, No. 5, pp. 1188-1191.

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