Method of therapeutically treating tissue while preventing...

Surgery – Instruments – Electrical application

Reexamination Certificate

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C607S101000, C607S105000

Reexamination Certificate

active

08007496

ABSTRACT:
A method of treating a tissue region (e.g., a tumor) is provided. The method comprises introducing a delivery sheath within an anatomical conduit that supplies the tissue region with a fluid (e.g., blood or air). The anatomical conduit may be any naturally occurring conduit within a patient. The method further comprises expanding an occlusive device (e.g., a balloon) associated with the delivery sheath, such that the conduit is at least partially occluded to reduce the flow of fluid through the conduit. The method further comprises introducing a tissue treatment catheter within the delivery sheath, advancing the treatment catheter from the delivery sheath through an aperture in a wall of the conduit adjacent the tissue region, and conveying thermal energy from (i.e., hyperthermia) or to the treatment catheter (i.e., hypothermia) to treat (e.g., by ablating) the tissue region.

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Oshima, Fumiyoshi et al., Lung Radiofrequency Ablation with and without Bronchial Occlusion: Experimental Study in Porcine Lungs, Journal of Vascular and Interventional Radiology 2003, vol. 15, No. 12, pp. 1451-1456, Dec. 2004.

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