Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing
Patent
1995-06-05
1996-12-03
Dees, Jose G.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
514114, 514381, 514535, 514562, 514563, 514649, G01N 33493
Patent
active
055805426
ABSTRACT:
Disclosed is an acetyltransferase activity measuring agent which contains an arylamine derivative. As the arylamine derivative, sodium p-aminohippurate can be used preferably. Use of the acetyltransferase activity measuring agent of this invention permits a simple and safe diagnosis of the progress of the pathema of nephritis, which is accompanied by a mesangial proliferative lesion, or renal insufficiency. Furthermore, the scattering of measured values is small, thereby assuring an accurate diagnosis.
REFERENCES:
Pacifici et al., Xenobiotica, 1988, vol. 18, No. 7, 849-856.
Cribb et al., The Journal of Pharmacology and Experimental Therapeutics, 259: 1241-1246 (1991).
Onodera Chikau
Yanaka Mikiro
Yoshihara Hiromi
Conrad, III Joseph M.
Dees Jos,e G.
Kureha Kagaku Kogyo K.K.
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