Method of testing for nephritis

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing

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514114, 514381, 514535, 514562, 514563, 514649, G01N 33493

Patent

active

055805426

ABSTRACT:
Disclosed is an acetyltransferase activity measuring agent which contains an arylamine derivative. As the arylamine derivative, sodium p-aminohippurate can be used preferably. Use of the acetyltransferase activity measuring agent of this invention permits a simple and safe diagnosis of the progress of the pathema of nephritis, which is accompanied by a mesangial proliferative lesion, or renal insufficiency. Furthermore, the scattering of measured values is small, thereby assuring an accurate diagnosis.

REFERENCES:
Pacifici et al., Xenobiotica, 1988, vol. 18, No. 7, 849-856.
Cribb et al., The Journal of Pharmacology and Experimental Therapeutics, 259: 1241-1246 (1991).

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