Method of targeting tumors in humans

Details Method of targeting tumors in humans Method of targeting tumors in humans

1988-12-01

1991-05-28

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 424450, 4284022, 436829, 600 3, A61K 4300, A61K 9133, A61K 4902

Patent

active

050193694

ABSTRACT:
A method is provided for delivering micellular particles containing a radiolabelled marker to tumors within humans. The micellular particles are less than approximately 2000.ANG. and incorporate essentially chemically pure phospholipid molecules in their external surface. Human patients given intravenous injections of such radiolabelled micellular particles showed tumors imaged by such method, without developing symptoms related to the micellular particles.

REFERENCES:
patent: 3992513 (1976-11-01), Petkau et al.
patent: 4086330 (1978-04-01), Petkau et al.
patent: 4310505 (1982-01-01), Baldeschwieler et al.
patent: 4310506 (1982-01-01), Baldeschwieler et al.
patent: 4429008 (1984-01-01), Martin et al.
patent: 4485054 (1984-11-01), Mezei et al.
patent: 4497791 (1985-02-01), Gamble et al.
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4581222 (1986-04-01), Baldeschwieler et al.
patent: 4588578 (1986-05-01), Fountain et al.
Proffitt et al., Journal of Nuclear Medicine, 24(1), pp. 45-51 (Jan. 1983).
Richardson et al., Journal of Nuclear Medicine, 19(9), pp. 1049-1054 (1978).
Wu et al., Proc. Natl. Acad. Sci. U.S.A., 78, pp. 2033-2037, (1981).
Mauk et al., Proc. Natl. Acad. Sci. U.S.A., 76, pp. 765-769, (1979).
H. I. Peterson, Vascular and Extravascular Spaces in Tumors: Tumor Vascular Permeability.
G. Gregoriadis, Liposomes in Biological Systems, Gregoriadis, Ed. Ch. 2 (1980).
B. Ryman et al., Biol. Cell, vol. 47, pp. 71-80 (1983).
G. Poste, Biol. Cell, vol. 47, pp. 19-38 (1983).
Mauk & Gamble, Anal. Biochem., 94, pp. 302-307 (1979).

Affiliated with

Also associated with

Rating

Method of targeting tumors in humans does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of targeting tumors in humans, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of targeting tumors in humans will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-35004