Method of targeting specific cell populations using...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S391900

Reexamination Certificate

active

07989598

ABSTRACT:
The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or tissue suspected of containing the selected cell population with a cell-binding agent maytansinoid conjugate, wherein one or more maytansinoids is covalently linked to the cell-binding agent via a non-cleavable linker and the cell-binding agent binds to cells of the selected cell population.

REFERENCES:
patent: 4137230 (1979-01-01), Hashimoto et al.
patent: 4248870 (1981-02-01), Miyashita et al.
patent: 4256746 (1981-03-01), Miyashita et al.
patent: 4260608 (1981-04-01), Miyashita et al.
patent: 4265814 (1981-05-01), Hashimoto et al.
patent: 4294757 (1981-10-01), Asai
patent: 4307016 (1981-12-01), Asai et al.
patent: 4308268 (1981-12-01), Miyashita et al.
patent: 4308269 (1981-12-01), Miyashita et al.
patent: 4309428 (1982-01-01), Miyashita et al.
patent: 4313946 (1982-02-01), Powell et al.
patent: 4315929 (1982-02-01), Freedman et al.
patent: 4317821 (1982-03-01), Miyashita et al.
patent: 4322348 (1982-03-01), Asai et al.
patent: 4331598 (1982-05-01), Hasegawa et al.
patent: 4361650 (1982-11-01), Asai et al.
patent: 4362663 (1982-12-01), Kida et al.
patent: 4364866 (1982-12-01), Asai et al.
patent: 4371533 (1983-02-01), Akimoto et al.
patent: 4424219 (1984-01-01), Hashimoto et al.
patent: 4450254 (1984-05-01), Isley et al.
patent: 5208020 (1993-05-01), Chari et al.
patent: 5416064 (1995-05-01), Chari et al.
patent: 5679648 (1997-10-01), McCaffrey et al.
patent: 6333410 (2001-12-01), Chari et al.
patent: 6441163 (2002-08-01), Chari et al.
patent: 6531131 (2003-03-01), Gu et al.
patent: 7097840 (2006-08-01), Erickson et al.
patent: 7276497 (2007-10-01), Chari et al.
patent: 7303749 (2007-12-01), Chari
patent: 7754211 (2010-07-01), Rosenblum et al.
patent: 2002/0001587 (2002-01-01), Erickson et al.
patent: 2004/0241174 (2004-12-01), Amphlett et al.
patent: 2003/259913 (2003-08-01), None
patent: 2003/247762 (2004-01-01), None
patent: 0 425 235 (1991-05-01), None
patent: 0 563 475 (1993-10-01), None
patent: 1 354 896 (2003-10-01), None
patent: 3-161490 (1991-07-01), None
patent: 98/20020 (1998-05-01), None
patent: 00/76554 (2000-12-01), None
patent: 01/00244 (2001-01-01), None
patent: 0124763 (2001-04-01), None
patent: WO 0124763 (2001-04-01), None
patent: 02/16429 (2002-02-01), None
patent: 02057316 (2002-07-01), None
patent: 02098883 (2002-12-01), None
patent: 03/000113 (2003-01-01), None
patent: 03/024392 (2003-03-01), None
patent: 03/057163 (2003-07-01), None
patent: 03/068956 (2003-08-01), None
patent: 03/074081 (2003-09-01), None
patent: 2004/005470 (2004-01-01), None
patent: 2004/016225 (2004-02-01), None
Roguska et al. (Protein Engineering 1996; 9: 895-904).
Queen et al. (PNAS 1989; 86: 10029-10033).
Michael A. Roguska, et al; A comparison of two murine monoclonal antibodies humanized by CDR-grafting and variable domain resurfacing; Protein Engineering vol. 9, No. 10 pp. 895-904, 1996.
Chari, et al. “Immunoconjugates Containing Novel Maytainsinoids: Promising Anticancer Drugs”, Cancer Research 52 , 127-133, Jan. 1, 1992.
Liu, et al. “Eradication of large colon tumor xenografts by targeted delivery of maytansinoids”, Proc. Natl. Acad. Sci. USA, vol. 93, pp. 8618-8623, Aug. 1996, Medical Sciences.
Akiyoshi Kawai, et al., “Chemical Modification of Ansamitocins. III. Synthesis and Biological Effects of 3-Acyl Esters of Maytansinol,” 1984, pp. 3441-3451, Chemical and Pharmaceutical Bulletin, vol. 32, No. 9.
Examiner's Report dated Aug. 21, 2009 issued in Australian Patent Application No. 2004282491.
Y. Arano, et al., “A newly designed radioimmuno-conjugate releasing a hippurate-like radiometal chelate for enhanced target
on-target radioactivity”, Nuclear Medicine and Biology, vol. 2, No. 1, pp. 63-69, Jan. 1, 1994.
P. R. Hamann, “Monoclonal Antibody-Drug Conjugates”, Expert Opinion on Therapeutic Patents, vol. 15, No. 9, pp. 1087-1103, Jan. 1, 2005.
L. Lam, et al., “Recent Advances in Drug-Antibody Immunoconjugates for the Treatment of Cancer”, Drugs of the Future, vol. 28, No. 9, pp. 905-910, Jan. 1, 2003.
Supplementary European Search Report dated Jul. 1, 2010, as issued in European Patent Application No. 04793896.4.
Liu, C. et al., “Cure of Human Small Cell Lung Cancer Xenografts in Scid Mice by a HN901-Maytansinoid Immunoconjugate”, Proceedings of the Annual Meeting of the American Association for Cancer Research, vol. 38, No. 190, p. 29, Jan. 1, 1997.
Liu, C. et al., “The Development of Antibody Delivery Systems to Target Cancer with Highly Potent Maytansinoids”, Expert Opinion on Investigational Drugs, vol. 6, No. 2, pp. 169-172, Feb. 1997.
Liu, C. et al., “Cure of Large Human Colon Xenografts by a C242-Maytansinoid Conjugate”, Proceedings of the Annual Meeting of the American Association for Cancer Research, vol. 37, pp. 466-467, Apr. 20, 1996.
Partial European Search Report dated Dec. 3, 2010, as issued in European Patent Application No. 10184672.3.
English translation of Japanese Office Action dated Jan. 4, 2011, as issued in Japanese Application No. 2006-533951.
English translation of Technical Report No. GLMR11/00004 received Apr. 6, 2011, as issued in Costa Rica Patent Application No. 8319.
Technical Report No. GLMR11/00004 received Apr. 6, 2011, as issued in Costa Rica Patent Application No. 8319.
Tolcher, Anthony W., et al., “Phase I Pharmacokinetic and Biologic Correlative Study of Mapatumumab, a Fully Human Monoclonal Antibody with Agonist Activity to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor-1”, Journal of Clinical Oncology, vol. 25, No. 11, pp. 1390-1396, Apr. 10, 2007.
U.S. Appl. No. 60/488,447, filed Jul. 21, 2003, Gillian Payne, et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of targeting specific cell populations using... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of targeting specific cell populations using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of targeting specific cell populations using... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2630769

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.