Method of T.sub.1 -weighted resonance imaging of RES organs

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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424 9323, 424646, 424648, A61B 5055

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active

058558683

ABSTRACT:
The invention provides a method of contrast enhanced MR angiography of the human or non-human animal body, said method comprising administering into the vasculature thereof a contrast effective amount of a contrast agent composition comprising magnetic particles having a r.sub.2 /r.sub.1 ratio of no more than 5, and, at a time when sufficient of said magnetic particles remain in the vasculature to provide positive contrast enhancement thereof in a T.sub.1 -weighted image while sufficient magnetic particles have been taken up into an organ of the reticuloendothelial system to provide negative contrast enhancement thereof in said T.sub.1 -weighted image, generating a T.sub.1 -weighted image magnetic resonance image of at least said organ.

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