Method of synthesizing sterically hindered 5-substituted-1H-tetr

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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544287, 544290, 548250, 548252, 548254, C07D23990

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active

055021913

ABSTRACT:
A method for making 5-substituted tetrazoles of formula I: ##STR1## where R is as herein described which comprises reacting a compound of the formula R--CN with a Lewis acid and an azide or a preformed metal azide complex, acidifying and recovering the 5-substituted tetrazole.

REFERENCES:
Advance Organic Chemistry, Jerry March, pp. 227-229, 1985.
Finnegan et al. J. Am. Chem. Soc., 80 pp. 3908-3911, 1958.

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