Method of synthesizing polynucleotides using ionic liquids

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S025330, C536S025340, C536S022100, C536S023100, C536S025400, C536S025410

Reexamination Certificate

active

06858720

ABSTRACT:
A method of synthesizing polynucleotides is disclosed. The method involves contacting a first nucleotide with a selected reactive group in the presence of an ionic liquid. The selected reactive group may be on a second nucleotide, a polynucleotide, or on a moiety on an insoluble substrate, for example in an oligonucleotide synthesizer.

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