Method of synthesizing optically active .beta.-halolactic acid

Details Method of synthesizing optically active .beta.-halolactic acid Method of synthesizing optically active .beta.-halolactic acid

1992-10-19

1994-06-21

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435123, 435139, 435183, 435195, 435280, 435877, C12P 742, C12P 756, C12P 1702, C12P 4100

Patent

active

053227824

ABSTRACT:
Optically active .beta.-halolactic acids can be produced by contacting an .alpha.,.beta.-dihalopropionic acid with 2-halo acid dehalogenase. When the pH of the reaction system is above 9, this process gives optically active glycidic acid. Treatment of the optically active .beta.-halolactic acid thus obtained with an alkali also gives optically active glycidic acid.

REFERENCES:
patent: 4247641 (1981-01-01), Neidleman et al.
patent: 4284723 (1981-08-01), Neidleman et al.
patent: 4758518 (1988-07-01), Taylor
patent: 4943528 (1990-07-01), Nakamura et al.
Biotechnology and Bioengineering, vol. 26, Jul. 1984, pp. 805-806.
Chemical Abstracts, vol. 97, 1982, p. 227, abstract No. 35149k.
Biological Abstracts, vol. 75, No. 10, 1983, p. 7807, abstract No. 75052.

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