Method of synthesis of plurality of compounds in parallel using

Details Method of synthesis of plurality of compounds in parallel using Method of synthesis of plurality of compounds in parallel using

1995-05-31

1997-07-01

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 253, 536 2531, 422131, 422134, 525 5411, C12Q 168, C07H 2100, C08F28300

Patent

active

056437382

ABSTRACT:
Methods are provided for synthesizing a plurality of compounds in parallel. The methods use cross-over channels for moving samples from a reservoir of starting materials into a plurality of wells. The movement is achieved, for example, using an electrokinetic pump.

REFERENCES:
patent: 3615241 (1971-10-01), Low et al.
patent: 4385115 (1983-05-01), de Zabala et al.
patent: 4676274 (1987-06-01), Brown
patent: 4753775 (1988-06-01), Ebersole et al.
patent: 4756884 (1988-07-01), Hillman et al.
patent: 4891120 (1990-01-01), Sethi et al.
patent: 4908112 (1990-03-01), Pace
patent: 4948961 (1990-08-01), Hillman et al.
patent: 4963498 (1990-10-01), Hillman et al.
patent: 4966646 (1990-10-01), Zdeblick
patent: 5006749 (1991-04-01), White
patent: 5026773 (1991-06-01), Steel
patent: 5037882 (1991-08-01), Steel
patent: 5053454 (1991-10-01), Judd
patent: 5073029 (1991-12-01), Eberly et al.
patent: 5140161 (1992-08-01), Hillman et al.
patent: 5141868 (1992-08-01), Shanks et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5144139 (1992-09-01), Hillman et al.
patent: 5147607 (1992-09-01), Mochida
patent: 5164598 (1992-11-01), Hillman et al.
patent: 5175209 (1992-12-01), Beattie et al.
patent: 5176203 (1993-01-01), Larzul
patent: 5194133 (1993-03-01), Clark et al.
patent: 5204525 (1993-04-01), Hillman et al.
patent: 5229297 (1993-07-01), Schnipelsky et al.
patent: 5237016 (1993-08-01), Ghosh et al.
patent: 5250263 (1993-10-01), Manz
patent: 5277754 (1994-01-01), Hadimioglu et al.
patent: 5288463 (1994-02-01), Chemelli
patent: 5288468 (1994-02-01), Church et al.
patent: 5296114 (1994-03-01), Manz
patent: 5304487 (1994-04-01), Wilding et al.
patent: 5324483 (1994-06-01), Cody et al.
patent: 5324633 (1994-06-01), Fodor et al.
patent: 5359115 (1994-10-01), Campbell et al.
patent: 5368823 (1994-11-01), McGraw et al.
patent: 5384261 (1995-01-01), Winkler et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5420328 (1995-05-01), Campbell
patent: 5424186 (1995-06-01), Fodor et al.
patent: 5463564 (1995-10-01), Agrafiotis et al.
patent: 5472672 (1995-12-01), Brennan
patent: 5474796 (1995-12-01), Brennan
patent: 5480614 (1996-01-01), Kamahori
Dasgupta, et al., Electroosmosis: A Reliable Flud Propulsion System for Flow Injection Analysis, Anal. Chem. 66:1792-1798, 1994.
Jacobson, et al., Precolumn Reactions with Electrophoretic Analysis Integrated on a Microchip, Anal. Chem. 66:4127-4132, 1994.
Richter, et al., A Micromachined Electrohydrodynamic (EHD) Pump, Sensors and Actuators A, 29:159-168, 1991.
Bart, et al., Microfabricated Electrohydrodynamic Pumps, Sensors and Actuators, A21-A23:193-197, 1990.
Melcher, Traveling-Wave Induced Electroconvection, The Physics of Fluids, 9:1548-1555, 1966.
Pickard, Ion Drag Pumping. I. Theory, J. Applied Physics 34:246-250, 1963.
Pickard, Ion Drag Pumping. II. Experiment, J. Applied Physics, 34:251-258, 1963.
Stuetzer, Ion Drag Pumps, J. Applied Physics, 31:136-146, 1960.
Petersen, Silicon as a Mechanical Material, Proceedings of The IEEE, 70:420-457, 1982.
Tracey, et al., Microfabricated Microhaemorheometer, pp. 82-84, 1991.
Medynski, Synthetic Peptide Combinatorial Libraries, Bio/Technology, 12:709-710, 1994.
Jacobson, et al., Effects of Injection Schemes and Column Geometry on the Performance of Microchip Electrophoresis Devices, Anal. Chem. 66:1107-1113, 1994.
Megregany, Microelectromechanical Systems, Circuits and Devices, Jul. 1993, pp. 14-22.
Fisher, Microchips for Drug Compounds, New York Times, Mar. 3, 1991.
Fodor, et al., Light-Directed, Spatially Addressable Parallel Chemical Synthesis, Science, 251:767-773, 1991.
The Silver Shotguns, The Economist, Dec. 14-20, 1991.
Howe, et al., Silicon Micromechanics; Sensors and Actuators on a Chip, IEEE Spectrum, Jul. 1990, pp. 29-35.
Angell, et al., Silicon Micromechanical Devices, Scientific American 248:44-55, 1983.
Andreas Manz et al., Trends in Analytical Chemistry, 10(5):144-148 (1991).

Affiliated with

Also associated with

Rating

Method of synthesis of plurality of compounds in parallel using does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of synthesis of plurality of compounds in parallel using , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of synthesis of plurality of compounds in parallel using will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-595845