Method of synthesis of hydroxy-substituted-4-alkoxyphenylacetic

Details Method of synthesis of hydroxy-substituted-4-alkoxyphenylacetic Method of synthesis of hydroxy-substituted-4-alkoxyphenylacetic

1989-03-03

1991-04-16

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 6501

Patent

active

050084496

ABSTRACT:
A process for preparing hydroxy-substituted-4-alkoxyphenylacetic acids by reacting a 4-alkoxyphenylacetic acid with bromine and then treating the brominated acid with a strong base and a copper salt to form the desired hydroxy-substituted-4-alkoxyphenylacetic acid.

REFERENCES:
patent: 1529946 (1925-03-01), Dubin et al.
patent: 2228920 (1941-01-01), Eckert et al.
patent: 2240275 (1941-04-01), Whitmore et al.
patent: 3086990 (1963-04-01), Reeve
patent: 4390723 (1983-06-01), Matsuno
Weller et al., J. Org. Chem., 49:2061-2063, (1984).

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