Method of synthesis for 6,9-bis[(2-aminoethyl)amino]benzo[g]isoq

Details Method of synthesis for 6,9-bis[(2-aminoethyl)amino]benzo[g]isoq Method of synthesis for 6,9-bis[(2-aminoethyl)amino]benzo[g]isoq

1995-06-07

1997-04-01

Davis, Zinna Northington

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D41914

Patent

active

056167091

ABSTRACT:
In the search for novel heteroanalogs of anthracendiones, 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimaleate salt (BBR 2778), was selected as the most promising compound. New methods of synthesis produce the compound in purity greater than 99%.

REFERENCES:
patent: 5506232 (1996-04-01), Spinelli et al.
Krapcho et al., J. Med. Chem., vol. 28, pp. 1124-1126, 1985.
Krapcho et al., J. Med. Chem., vol. 37, pp. 828-837, 1994.

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