Method of suppressing water resonance in a magnetic proton reson

Details Method of suppressing water resonance in a magnetic proton reson Method of suppressing water resonance in a magnetic proton reson

1989-11-15

1991-08-20

Williams, Hezron E.

Electricity: measuring and testing

Particle precession resonance

Using a nuclear resonance spectrometer system

324307, G01R 3320

Patent

active

050417878

ABSTRACT:
A magnetic resonance method for in vivo measurement of water-suppressed localized proton spectra, and device for performing the method, utilizes a frequency selective adiabatic fast passage pulse to achieve water suppression. Subsequent to a waiting period after the adiabatic pulse, during which selectively excited water magnetization has longitudinally relaxed until the longitudinal water magnetization has reached an amplitude of zero, an echo resonance signal in which water has been suppressed is generated by means of a volume-selective Hahn spin echo sequence. A spectrum is determined from the echo resonance signal by way of Fourier transformation. The method is particularly suitable for in vivo use in conjunction with surface coils where the rf electromagnetic field is liable to exhibit a substantial inhomogeneity. Comparatively small volumes can be measured by combination with a Hahn spin echo sequence, the overall examination time during in vivo measurement remaining within acceptable limits, for example during spectroscopic imaging.

REFERENCES:
patent: 4771242 (1988-09-01), Lampman et al.
patent: 4947119 (1990-08-01), Ugurbil et al.
patent: 4962357 (1990-10-01), Sotak
K. Ugurbil et al., "Optimization of Modulation Functions to Improve Insensitivity of Adiabatic Pulses to Variations in B.sub.1 Magnitude", Journal of Magnetic Resonance, vol. 80, No. 3, Dec. 1988, pp. 448-469.

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