Method of suppressing the thermal degradation of urokinase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...

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435215, 435236, C12N 996, C12N 972

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active

049467859

ABSTRACT:
The thermal degradation of urokinase in an aqueous solution is suppressed by heating an aqueous solution containing urokinase in the presence of citric acid or a water-soluble salt thereof such as sodium, potassium or lithium citrate at about 60.degree. C. for about 10 hours.

REFERENCES:
patent: 4361652 (1982-11-01), Uemura et al.
patent: 4404187 (1983-09-01), Schwinn et al.

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