Method of suppressing appetite by administration of tetrahydro-b

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514909, A61K 3144

Patent

active

049786695

ABSTRACT:
Compounds of formula I are useful for suppressing appetite, for altering macronutrient preferences, for suppressing obsessive-compulsive behavior, and for inhibiting cravings and substance abuse: ##STR1## wherein R.sub.1 and R.sub.3 are each independently H, hydroxy-alkyl, alpha-cyanoalkyl, SO.sub.3 H, SO.sub.2 NH.sub.2, or C(O)R, where R is OH, NH.sub.2, lower alkoxy, benzyloxy, or aliphatic amino acyl;

REFERENCES:
patent: 3294809 (1966-12-01), Shaveh, Jr.
patent: 4336260 (1982-06-01), Payne et al.
Glassman et al., Science, vol. 226, 1984, pp. 864-866.
Airaksinen et al., Med. Biol., 1981, 59:190-211.
Huttunen et al., Pharmacol. Biochem. & Behav., (1986), 24:1773-1778.
Rommelspacher et al., Naunyn-Schiedeberg's Arch. Pharmacol., (1977), 298:83-91.
Cooper, Eur. J. Pharmacol., (1986), 120:257-265.
Skonick et al., "Beta-Carbolines and Tetrahydroisquinolines", A. R. Liss, editor, New York, (1982), pp. 233-252.
Robertson et al., Eur. J. Pharmacol., (1981), 76:281-284.
Greiner et al., Naunyn-Schmiedberg's Arch. Pharmacol., (1983), 322:140-146.
Cain et al., J. Med. Chem., (1982), 25(9):1981-1091.
Koho, Chem. Abstracts, (1981), 95:705, Abstract No. 115508a.
Koho, Chem. Abstracts, (1984), 101:655, Abstract No. 110890b.
Ikuo et al., Chem. Abstracts, (1986), 105:726, Abstract No. 191049s.
Haffer et al., Chem. Abstracts, (1987), 106:604.
Shavel, Chem. Abstracts, (1967), 66:7128, Abstract No. 75985w.
Ikuo et al., Chem. Abstracts, (1985), 103:711 Abstract No. 160488p.
Biere, Chem. Abstracts, (1984), 101:643, Abstract No. 72711j.
Koho, Chem. Abstracts, (1983), 98:639, Abstract No. 126057r.
Koho, Chem. Abstracts, (1982), 96:771, Abstract No. 218092k.
Neef et al., Chem. Abstracts, (1983), 98:510, Abstract No. 16663c.
Langbein et al., Chem. Abstracts, (1972), 77:399, Abstract No. 126602f.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of suppressing appetite by administration of tetrahydro-b does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of suppressing appetite by administration of tetrahydro-b, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of suppressing appetite by administration of tetrahydro-b will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1425797

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.