Method of stimulating the growth of macrophage-like cells utiliz

Details Method of stimulating the growth of macrophage-like cells utiliz Method of stimulating the growth of macrophage-like cells utiliz

1987-01-07

1987-11-03

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514885, 424101, A61K 3702

Patent

active

047043806

ABSTRACT:
Novel tetradecapeptides having the following sequence were found to have potent mitogenic activity for machropage-like cells:

REFERENCES:
patent: 4376071 (1983-03-01), Jennings et al.
Bar-Shavit et al., "Identification of a Thrombin Sequence with Growth Factor Activity on Macrophages" Proc Natl Acad Sci USA vol. 83, pp. 976-980, Feb. 1980.
Perdue, J. Biol. Chem. 256, 2767-2776 (1981).
Bar-Shavit et al., J. Cell Biol. 96, 282-285 (1983).
Bar-Shavit et al., Science 220, 728-730 (1983).
Bar-Shavit et al., J. Cell Biol. 97, 396a, Abstract 1494 (1983).
Bar-Shavit et al., J. Cell Biol. Chem. 252, 4942-4957 (1977).
Butkowski et al., J. Biol. Chem. 252, 4942-4957 (1977).
Bar-Shavit et al., Biochemistry 23(3) 397-400 (1984).

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