Method of stimulating myelination of cells

Details Method of stimulating myelination of cells Method of stimulating myelination of cells

1994-10-20

1996-11-12

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 13, 530324, 530326, A61K 3800, A61K 3802, C07K 500, C07K 700

Patent

active

055740090

ABSTRACT:
The present invention provides methods for treating mammalian diseases and conditions characterized by myelin destruction. The present invention provides methods for inducing myelin formation by myelin forming cells expressing reovirus type 3 receptors comprising administering to such cells an effective amount of a compound bindable with the reovirus type 3 receptor. The compounds for use in the method of the invention preferably comprise antibodies and peptides, more preferably synthetic peptides.

REFERENCES:
patent: 4230696 (1980-10-01), Hashim
patent: 4615884 (1986-10-01), Harshman et al.
patent: 5003044 (1991-03-01), Hunter et al.
patent: 5219837 (1993-06-01), Cohen et al.
Ventimiglia, R., et al., "Localization of .beta.-adrenaergic receptors on differentiated cells of the central nervous system in culture," Proc. Natl. Acad. Sci. USA 84:5073-5077, 1987.

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