Method of stabilizing tretinoin

Details Method of stabilizing tretinoin Method of stabilizing tretinoin

1990-04-18

1991-08-06

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424333, 514546, 514557, 568824, A61F 200

Patent

active

050376551

ABSTRACT:
A tretinoin-mineral oil-petrolatum product in which the ingredients are blended at about 90.degree. C., which product retains its therapeutic activity despite storage at ambient conditions without the need for an antioxidant.

REFERENCES:
patent: 3906108 (1975-09-01), Felty
patent: 4022913 (1977-03-01), Newmark
patent: 4034114 (1977-07-01), Yu
patent: 4247547 (1981-01-01), Marks
patent: 4254100 (1981-03-01), Keller
patent: 4840970 (1989-06-01), Ohasi
Merck Index 10th Ed., p. 8064 (1983).

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