Method of stabilizing pharmaceutical preparations comprising dig

Details Method of stabilizing pharmaceutical preparations comprising dig Method of stabilizing pharmaceutical preparations comprising dig

1997-08-22

1999-11-30

Lankford, Jr., Leon B.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Stabilized enzymes or enzymes complexed with nonenzyme

424 942, 424 9421, 424428, 424550, 424556, A61K 3854, A61K 3539, A61K 3537, A61F 200

Patent

active

059938064

ABSTRACT:
The use of complex lipids, especially lecithin, as additives to stabilize water-soluble pharmaceutical preparations of digestive enzyme mixtures containing lipases and proteases, especially pancreatin-containing digestive enzyme mixtures, which are suitable for preparing aqueous solutions for continuous introduction into the gastrointestinal tract by means of a tube, against a decrease in lipolytic activity under the influence of moisture.

REFERENCES:
patent: 3956483 (1976-05-01), Lewis
patent: 3991180 (1976-11-01), Boettner et al.
patent: 4019958 (1977-04-01), Hell et al.
patent: 4242219 (1980-12-01), Bogerman et al.
DeRobertis. Cell and Molecular Biology, 7th ed. pp. 132-133, 1980.
Chemical Abstracts, No. 99: 200535j entitled "Capsules Containing Stable Digestive Enzymes", vol. 99 (1983) p. 342.

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