Method of solid cancer tumor treatment using isopropylpyrrolizin

Details Method of solid cancer tumor treatment using isopropylpyrrolizin Method of solid cancer tumor treatment using isopropylpyrrolizin

1985-12-03

1988-03-29

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3140

Patent

active

047344237

ABSTRACT:
This invention provides a method of providing treatment to a warm blooded animal in need of treatment of a solid cancer tumor comprising administering an effective amount of a isopropylpyrrolizine of the formula: ##STR1##

REFERENCES:
Instruction 14 Screening Data Summary Interpretation and Outline of Current Screen, (National Cancer Institute).
Cancer Treatment Reports, vol. 66, No. 1, Jan. 1982, (Wayne K. Anderson et al.).
Jour. Organic Chemistry, 1977, 42, 599, (Anderson).
Jour. Med. Chemistry, 1977, 20 812, (Anderson).
Jour. Med. Chemistry, 1977, 20 1691, (Anderson).
Journal of Med. Chemistry, 1979, 22, 977, (Anderson).
Jour. Med. Chemistry, 1980, 23 87, (Anderson).
Jour. of Heterocyclic Chemistry, 1980, 17, 513, (Anderson).
Reprint of Arzneimittel-Forschung/Drug Res. 30 (1), 5, 765-767, (1980).
Jour. Med. Chemistry, 1982, 25, 84, (Anderson).
Publication in Jun., 1982, Issue of Cancer Research, (Anderson), Title: The Activity of Bis-Carbamoyloxymethyl Derivatives of Pyrroles and Pyrrolizines Against Human Tumor Xenografts . . .
Grant Applns. CA 22935-01 through -06, Vinylogous Carbinolamine Tumor Inhibitors, (Principal Investigator: W. K. Anderson).
Chemical Structures of Interest to the Division of Cancer Treatment, Apr. 1981, pp. 1, 2, 9 and 19-22, (Author Unknown).
Screening Data Summary, Jun. 11, 1981, (National Cancer Institute).

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