Method of skin regeneration using a collagen-glycosaminoglycan m

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Hair or skin

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435371, 435360, 424426, A61F 210

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057164118

ABSTRACT:
The present invention relates to a method of skin regeneration of a wound or burn in an animal or human. This method comprises the steps of initially covering the wound with a collagen glycosaminoglycan matrix, allowing infiltration of the grafted GC matrix by mesenchymal cells and blood vessels from healthy underlying tissue and applying a cultured epithelial autograft sheet grown from epidermal cells taken from the animal or human at a wound free site on the animal's or human's body surface. The resulting graft has excellent take rates and has the appearance, growth, maturation and differentiation of normal skin.

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