Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Reexamination Certificate
2007-06-29
2011-11-15
Kosar, Andrew D (Department: 1622)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
C530S409000, C554S049000, C435S023000
Reexamination Certificate
active
08058409
ABSTRACT:
A means for pre-treatment in glycomic analysis of a glycoprotein is provided by the present invention.A salt of the general formula (I):wherein Z, X, R1, R2, M, m and n are the same as described in DESCRIPTION,is useful as a protein solubilizer, and an oligosaccharide is efficiently released from a sample if reductive alkylation and/or digestion by a proteinase are carried out under the presence of the said solubilizer at the first step in the glycomic analysis of glycoprotein derived from a living body.
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Furukawa Jun-ichi
Kita Yoko
Miura Yoshiaki
Nakano Mika
Nishimura Shin-Ichiro
Cutliff Yate K
Kosar Andrew D
National University Corporation Hokkaido University
Shionogi & Co. Ltd.
Wenderoth , Lind & Ponack, L.L.P.
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