Method of separating components in a sample using...

Details Method of separating components in a sample using... Method of separating components in a sample using...

2008-05-20

2008-05-20

Drodge, Joseph (Department: 1797)

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

C210S656000, C210S679000, C210S767000, C436S177000

Reexamination Certificate

active

07374684

ABSTRACT:
The present invention provides methods for separating one or more components of interest from a sample containing particulates and soluble materials. The method comprises the steps of: (a) filtering a sample through silica filter media whose surface silanol groups have reacted with one or more silanes, and (b) simultaneously capturing particulates and binding a soluble component to the silica filter media. The bound soluble component of interest is subsequently eluted from the silica filter media. In one embodiment of the invention, unwanted soluble materials are captured by the treated silica filter media and desired component of interest is recovered from the flow-through. In another embodiment, different components of interest are recovered from both the eluate and the flow-through. Preferred treated silica filter media are silane-treated rice hull ash or diatomaceous earth with functional quarternary ammonium group or functional sulphonate group. Particulates suitable for the present invention, for example, are microorganisms.

REFERENCES:
patent: 3680699 (1972-08-01), MacPherson
patent: 3810843 (1974-05-01), Sluzarczuk et al.
patent: 3865728 (1975-02-01), Abbott et al.
patent: 4187120 (1980-02-01), Kunin et al.
patent: 4238334 (1980-12-01), Halbfoster
patent: 4290892 (1981-09-01), Abbott
patent: 4298500 (1981-11-01), Abbott
patent: 4322542 (1982-03-01), Abbott
patent: 4379931 (1983-04-01), Plueddemann
patent: 4473474 (1984-09-01), Ostreicher et al.
patent: 4515821 (1985-05-01), Armstead et al.
patent: 4571389 (1986-02-01), Goodwin et al.
patent: 4594158 (1986-06-01), Chong et al.
patent: 4619911 (1986-10-01), Goodwin et al.
patent: 4645567 (1987-02-01), Hou et al.
patent: 4645605 (1987-02-01), Durham
patent: 4682992 (1987-07-01), Fuchs
patent: 4734208 (1988-03-01), Pall et al.
patent: 4824578 (1989-04-01), Schneider et al.
patent: 5019173 (1991-05-01), Gettings et al.
patent: 5073281 (1991-12-01), Paules et al.
patent: 5277813 (1994-01-01), Feibush et al.
patent: 5360633 (1994-11-01), Dean
patent: 5413059 (1995-05-01), Schips
patent: 5628910 (1997-05-01), Michos
patent: 5776353 (1998-07-01), Palm et al.
patent: 5856429 (1999-01-01), Michos
patent: 5858911 (1999-01-01), Wellen et al.
patent: 5888397 (1999-03-01), Rogers et al.
patent: 5942115 (1999-08-01), Rieber
patent: 6001406 (1999-12-01), Katzke et al.
patent: 6071410 (2000-06-01), Nau et al.
patent: 6375735 (2002-04-01), Stephens et al.
patent: 6482324 (2002-11-01), Kirkland et al.
patent: 6521290 (2003-02-01), Kudo et al.
patent: 6524489 (2003-02-01), Palm et al.
patent: 6713643 (2004-03-01), Pinnavala et al.
patent: 6749813 (2004-06-01), David et al.
patent: 2002/0070168 (2002-06-01), Jiang et al.
patent: 0 183 139 (1985-11-01), None
patent: 0 798 003 (1997-03-01), None
patent: 0 806 474 (1997-05-01), None
patent: 5212241 (1993-08-01), None
patent: 8119619 (1996-05-01), None
patent: 10036705 (1998-02-01), None
patent: 22146232 (2002-05-01), None
patent: WO 97/43401 (1997-03-01), None
patent: WO 00/48706 (2000-02-01), None
patent: WO 01/12296 (2001-02-01), None
patent: WO 02/083270 (2002-10-01), None
Roy, et al., “Preparation of Ion-Exhange Silica and Effect of pH on Protein Binding of Ion-Exchange Silica”,J. of Chromatographic Science, 22: 84-6 (1984).
Snyder, et al., “Preparation and Properties of Bonded-Phase Peckings”,Introduction to Modern Liquid Chromatography, 2ndedition, pp. 272-80 (1979).
Buszewski et al, “Survey and Trends in the Preparation of Chemically Bound Silica Phases for Liquid Chromatographic Analysis,” Journal of High Resolution Chromatography, vol. 21, May 1988, pp. 267-281, downloaded Nov. 9, 2005.
Int'l Search Report, PCT/US03/31629, Mailed Apr. 6, 2004.

Affiliated with

Also associated with

Rating

Method of separating components in a sample using... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of separating components in a sample using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of separating components in a sample using... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2785767