Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Patent
1990-08-30
1992-03-10
Lacey, David L.
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
356408, 25022723, 2504581, G01N 2176
Patent
active
050949586
ABSTRACT:
A chemical sensor, such as a fiber optic chemical sensor, is self-calibrated by measuring two output values which behave differently in response to an analyte, and forming a ratio between the two measured output values to cancel out effects of variations in external factors such as temperature variations, differences between coatings, light (illuminator) variations, fouling, bleaching, leaching or the like. An indicator material may be used which produces both fluorescence and phosphorescence, both monomer and aggregate emission or absorption bands, emission or absorption bands with or without an isosbestic point, emission peaks at one wavelength at two different excitation bands, or emission peaks at two wavelengths for excitation at two wavelengths.
REFERENCES:
patent: 4792689 (1988-12-01), Peterson
patent: 4924870 (1990-05-01), Wlodarczyk et al.
patent: 4945171 (1990-07-01), Haughland et al.
patent: 4954435 (1990-09-01), Krauth
Goswami, K.; Kennedy, J. A.; Dandge, D. K.; Klainer, S. M.; "A Fiber Optic Chemical Sensor for Carbon Dioxide Dissolved in Sea Water", SPIE, vol. 1172, Chemical, Biochemical, and Environmental Sensors, 1989, pp. 225-232.
Goswami Kisholoy
Klainer Stanley M.
Daley Thomas E.
FiberChem Inc.
Lacey David L.
Sartorio Henry P.
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